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Saturday, May 25, 2019

NEWS 25 MAY 2019

NEWS FROM USA

NEW GENERICS LAUNCHES IN US

DRUG

COMPANY

Corresponding RLD

Annual sales quoted in press release as per IQVIA 

Press Release

Budesonide inhalation suspension

Lupin

Pulmicort Repsules

(Astra Zeneca)

$385.4 Million

Link

Solifenacin Succinate tablets

Apotex

Vesicare

(Astellas)

N/A

Link

 

NDA APPROVALS

Approval Date

Product Name

NDA Sponsor

Brand Name

Prescribing information

23 May 2019

Alpelisib tablets

Novartis

Piqray

Link

 

505(b)2 APPROVALS

Approval Date

Product Name

NDA Sponsor

Brand Name

Prescribing information

23 May 2019

Drospirenone 4mg tablets

Exeltis

(Insud Pharma)

Slynd*

Link

20 May 2019

Fulvestrant injection#

Fresenius Kabi 

N/A

N/A

 

*Difference between Yaz and Slynd

-      Yaz contains combination of Drospirenone (3mg) and Ethinyl Estradiol (0.02mg), while Slynd contains only Drospirenone (4mg).

-      Both of them are used for contraception.

-      Dosing pattern of Slynd is similar to Yaz that includes administration of Drospirenone containing tablets once daily for 24 days followed by administration of placebo tablets for 4 days.

-      Yaz prescribing information: Link

-      Slynd Prescribing information: Link

 

#US granted patents on Fulvestrant by Fresenius

-      US 10188663; US 9833459; US 9271990

Tentative 505(b)2 APPROVALS

Approval Date

Product Name

NDA Sponsor

Brand Name

Prescribing information

23 May 2019

Pemetrexed disodium injections

Biocon

N/A

N/A

 

505(b)2 IN PIPELINE

Ethinyl Estradiol/Levonorgestrol Transdermal patch (Agile therapeutics): Agile Therapeutics Announces FDA Acceptance of the NDA Resubmission of Ethinyl Estradiol/Levonorgestrol Transdermal patch (Twirla)

-         Agile Therapeutics  announced that the U.S. Food and Drug Administration (FDA) has accepted for review the Company’s New Drug Application (NDA) resubmission for Twirla® (AG 200-15). It’s a hormonal contraceptive patch.

-         PDUFA goal date is 16 Nov. 2019.

-         The patch is designed to apply once weekly for three weeks, followed by a week without patch.

-         Full Press release: Link

AV001- injectable unapproved marketed product (Avadel Pharmaceuticals): Avadel Pharmaceuticals Announces FDA Acceptance of New Drug Application for AV001

-         Avadel Pharmaceuticals announced that the USFDA has accepted the New Drug Application (NDA) for the Company’s fourth Hospital Product, AV001.

-         It’s a sterile injectable unapproved marketed drug for which Avadel has submitted 505(b)2 NDA application.

-         As per company’s press release, subsequent to their NDA submission, the FDA granted an NDA approval for a parenteral product with the same Active Pharmaceutical Ingredient (API) as AV001.

-         PDUFA goal Date: September 15, 2019.

-         Press  Release: Link

ANDA APPROVALS

 

Approval Date

Drug Product

ANDA

Sponsor

Corresponding RLD

Number Of Other Approved Generics

17 May 2019

Amphetamine Aspartate; Amphetamine Sulfate; Dextroamphetamine Saccharate; Dextroamphetamine Sulfate ER Capsules

Rhodes Pharms

Adderall XR

(Shire)

Seven

20 May 2019

Dactinomycin Injection

X-Gen Pharms 

Cosmegen

(Recordati)

One

(Mylan)

20 May 2019

Albendazole Tablets

Actavis 

Albenza

(Impax)

Four

20 May 2019

Solifenacin Succinate Tablets

Watson Labs 

Vesicare

(Astellas)

More Than 10

20 May 2019

Solifenacin Succinate Tablets

Alembic Pharms

20 May 2019

Solifenacin Succinate Tablets

Glenmark 

20 May 2019

Solifenacin Succinate Tablets

Qilu Pharm 

20 May 2019

Solifenacin Succinate Tablets

Amneal Pharms 

20 May 2019

Solifenacin Succinate Tablets

Breckenridge Pharm

20 May 2019

Solifenacin Succinate Tablets

Cipla

20 May 2019

Solifenacin Succinate Tablets

Alkem 

20 May 2019

Solifenacin Succinate Tablets

Jiangxi Boya 

20 May 2019

Solifenacin Succinate Tablets

Airis Pharma 

20 May 2019

Solifenacin Succinate Tablets

Msn Labs 

20 May 2019

Solifenacin Succinate Tablets

Sciegen P

20 May 2019

Methylprednisolone Acetate injection

Amneal Pharms 

Depo-Medrol

(Pharmacia And Upjohn)

Five

21 May 2019

Dalfampridine ER Tablets

Sun Pharm

Ampyra

(Acorda)

Six

22 May 2019

Esomeprazole Magnesium DR Pellets Capsules

Zydus

Nexium

(Astrazeneca)

Ten

22 May 2019

Phytonadione Injection

Dr Reddys 

N/A

One

(Hospira)

22 May 2019

Trientine Hydrochloride Capsules

Msn Labs 

Syprine

(Aton)

Four

22 May 2019

Cyproheptadine Hydrochloride Syrup

Quagen

N/A

Five

 

 

TENTATIVE ANDA APPROVALS

Approval Date

Drug

Company

16 May 2019

Cabazitaxel

Mylan

16 May 2019

Rivaroxaban

Prinston 

16 May 2019

Dolutegravir

Laurus  Labs

20 May 2019

Pemetrexed 

Teva Pharms 

20 May 2019

Dimethyl Fumarate

Sun Pharm 

20 May 2019

Solifenacin Succinate

Ajanta Pharma

22 May 2019

Erlotinib

Accord Hlthcare 

If you have any query/suggestion then please write us at pharmacaption@gmail.com

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